2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-A0260
    Ethyl biscoumacetate 548-00-5 98%
    Ethyl biscoumacetate is an anticoagulant and vitamin K antagonist. Ethyl biscoumacetate can be used in the research of experimental venous thrombosis.
    Ethyl biscoumacetate
  • HY-A0300
    Cyclopeptide-5 197172-76-2 98%
    Cyclopeptide-5 (EMD 270179) is an αvβ3 antagonist that can improve PAF-induced increased adhesion of sickle red blood cells, capillary post-obstruction, and enhance blood flow dynamics. Cyclopeptide-5 also has cytotoxic effects.
    Cyclopeptide-5
  • HY-B0431
    Phenoxybenzamine 59-96-1 98%
    Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity.
    Phenoxybenzamine
  • HY-B0670
    Dihydroergotamine 511-12-6 98%
    Dihydroergotamine (DFN-19) is a BBB-permeable and semisynthetic, hydrogenated ergot alkaloid. Dihydroergotamine can cause vasoconstriction by stimulating alpha-adrenergic and 5-HT2A receptors. Dihydroergotamine can be used in the research of migraine.
    Dihydroergotamine
  • HY-B1001
    Todralazine 14679-73-3 98%
    Todralazine (Ecarazine) is an anti-hypertensive agent, acts as a β2AR blocker, with antioxidant and free radical scavenging activity.
    Todralazine
  • HY-B1254
    Altizide 5588-16-9 99.94%
    Altizide (Althiazide) is an orally active diuretic. Altizide can be used in studies of oedema and hypertension.
    Altizide
  • HY-B1416
    Efaroxan 89197-32-0 98%
    Efaroxan is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan is a selective I1-Imidazoline receptor antagonist. Efaroxan can be used for the research of cardiovascular disease.
    Efaroxan
  • HY-B1562
    Bopindolol 62658-63-3 98%
    Bopindolol ((±)-Bopindolol) is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol is a proagent of Pindolol (HY-B0982). Bopindolol can be used for essential and renovascular hypertension research.
    Bopindolol
  • HY-B1656
    Fomocaine 17692-39-6 98%
    Fomocaine (P 652) is an orally active local agent that can suppress or relieve pain. Fomocaine shows antiarrhythmic activity.
    Fomocaine
  • HY-B1660
    Guanadrel sulfate 22195-34-2 98%
    Guanadrel sulfate is an orally active, potent and postganglionic sympathetic inhibitor. Guanadrel sulfate lowers blood pressure by reducing systemic vascular resistance with little effect on cardiac output. Guanadrel sulfate is promising for research of hypertension.
    Guanadrel sulfate
  • HY-B1661
    Hexamethonium chloride 60-25-3 98%
    Hexamethonium Chloride Dihydrate is a synthetic organic compound commonly used as a ganglion blocking agent, which means it blocks the transmission of nerve impulses between ganglion cells in the autonomic nervous system. Hexamethonium Chloride Dihydrate is used in various medical applications such as lowering blood pressure or inhibiting certain types of neuropathic pain. It works by inhibiting the release of acetylcholine, a neurotransmitter that plays a key role in regulating many bodily functions.
    Hexamethonium chloride
  • HY-B1708
    Nordefrin 74812-63-8 98%
    Nordefrin ((±)-Cobefri), a Norepinephrine (HY-13715) derivative, is a vasoconstrictor agent.
    Nordefrin
  • HY-B2081
    Etozolin 73-09-6 98%
    Etozolin (W-2900A) is a diuretic agent. Etozolin inhibits fluid and electrolyte reabsorption in the loop of Henle. Etozolin can be used in research of congestive heart failure, hypertension and edema.
    Etozolin
  • HY-B2096
    Oleic acid ethanolamine 2272-11-9 98%
    Oleic (9-cis-Octadecenoic) acid ethanolamine consists of oleic acid and ethanolamine. Oleic acid ethanolamine has sclerotherapeutic activity. Oleic acid ethanolamine can cause inflammatory reaction in the intimal endothelium of the vein.
    Oleic acid ethanolamine
  • HY-B2105
    Erythrityl tetranitrate 7297-25-8 98%
    Erythrityl tetranitrate (Tetranitrate; Nitroerythrite), a nitrate ester, is a long-acting vasodilator with properties similar to nitroglycerin. Erythrityl tetranitrate decreases the counter load of the heart and improvement of the pump function of left ventricle in an acute experiment in case of chronic cardiac insufficiency with stasis.
    Erythrityl tetranitrate
  • HY-D1073
    DiOC7(3) 53213-83-5 98%
    DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities.
    DiOC7(3)
  • HY-D1408
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite 1260508-74-4 98%
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
  • HY-D1409
    DMTr-4'-F-U-CED-TBDMS phosphoramidite 98%
    DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-F-U-CED-TBDMS phosphoramidite
  • HY-D2975
    TTVP
    TTVP is a high-performance, blood activated AIE near-infrared fluorescent probe. TTVP can display hemorrhagic areas in the mouse brain with ultra sensitivity and high contrast specificity. TTVP provides a visual assessment tool for the study of hemorrhagic conditions.
    TTVP
  • HY-D2976
    CN-N2 51347-92-3
    CN-N2 is a visible light fluorescent probe. CN-N2 has high selectivity, rapid penetration, good biocompatibility, and imaging effects. CN-N2 is suitable for intraoperative rapid imaging of atherosclerotic plaque.
    CN-N2
Cat. No. Product Name / Synonyms Application Reactivity